Unlike MAXSHIFT algorithm of JPEG2000,by combining coding and embedded zerotree wavelet(EZW),a novel regions of interest(ROI) algorithm based on residue image called RZ was presented in this paper.The RZ algorithm is based on integer wavelet transform(IWT).The residue image of ROI based on high compressionm ratio EZW is coded by embedded zerotree coding based on integer square quantization threshold.The entropy coding was given to the residue data and the result was transmitted after original coding data.This algorithm can realize the lossless or near lossless ROI coding.The experiment results demonstrate RZ algorithm realizes ROI coding of low complication based on EZW framework and is applied to image transmission based on net.