This paper mainly introduces the I^2C control core, which is embedded in a controller for five inches color AMOLED. The agreement of I^2 C and embedding method in FPGA are discussed. The function of I^ C in this paper is to re alize the configuration of multi-standard decode chip whose types are AL 251 ,SAA 7111A and AD9882. And the simulation results and the results tested by oscillograph on 12 C control core are provided.