In this paper,the experiment and simulation analysis in time and frequency domains of the noise and interference in indoor visible light communication are accomplished.The influence of background noise and interference on the signal transmission of different rates is analyzed in simulations.It can be seen that the noise and interference can be taken as certain current and periodical interference signal,and the signal with low transmission rate can be interferred more easily.We compare the effects of the low pass filter which is used to filter the periodical interference signal at different data rates.Also,the power spectrum densities of some modulation schemes are demonstrated.The results show that the pulse position modulation and the Manchester code are more suitable for indoor visible light communication than other modulations,because of their less low-frequency components.