A novel approach to generate sextupling tunable millimeter-wave(mm-wave) signals is proposed and experimentally demonstrated based on a Mach-Zehnder modulator(MZM) and a Brillouin-assisted sideband-filtering technique.In this scheme,the dc bias is tuned for the MZM to suppress even sideband,with odd sideband left.The power of two first-order sidebands can be higher then the Brillouin threshold after the Er3+-doped fiber amplifier(EDFA).Using the 25 km-long sigle-mode fiber(SMF) as Brillouin medium,first-order sidebands are filtered,with three-order sidebands left.Finally,the sextupling mm-wave signals can be achieved by the amplifying of EDFA and the optic-electric conversion of photo-detector(PD).As this stimulated Brillouin scattering(SBS)-assisted sideband-filter is narrow band filtering,independent of wavelength,a wavelength-flexible way of optical mm-wave signal generaton can be successfully realized.