Abstract:High-resolution 3D visualization of vessels can help in the hepatic fibrosis diagnosis.X-ray phase-contrast imaging(PCI) is a new emerging imaging technique which provides high contrast and high resolution of biological soft tissues compared with conventional radiography.PCI-CT can produce 3D volumetric images of liver vessels and can be used for investigating micro-structures of vessels.In this paper,3D visualization of vessels in mild and severe liver fibrosis samples is presented by use of PCI-CT respectively,and textures of their inner walls are measured and analyzed.Moreover,the thromboses of chosen vessel segment in severe liver fibrosis sample are obtained and analyzed.The results show that PCI-CT clearly depicts the 3D micro-structures of vessels from different liver fibrosis degrees,and accurately reveals structures of vessel inner wall and thrombus.Thus,PCI-CT holds great promise for hepatic fibrosis diagnosis.