Chalcogenide glass micro-structure optical fibers (CGMOFs) have wide p otential applications in the field of infrared laser energy transmission and infrared optical fiber se nsing for their unique optical properties.The problem is that there is no good method to prepare chalcogenide g lass micro-structure optical fibers up to now.In this paper,we attempt to fabri cate chalcogenide glass micro-structure optical fibers by using the press formi ng method.A glass extruder is designed to extrude Ge₂₀Sb₁₅Se₆₅ chalcogenide glass into a multi-hole fiber preforms.Then,the extruder preform is drawn into fiber using an improved fiber drawing machine.The infrared transmi tting property is measured by using infrared thermal imager and infrared spectro meter.The optical loss of extruded glass is calculated based on the infrared tra nsmission spectra of glass disks with different thicknesses.We also measure fib e r cross-section and its diameter by scanning electron microscope (SEM).The resu lts show that the infrared transmission spectra of the extruded glass have not d ecreased obviously.The optical losses of the glasses before and after extruding at 10μm are 0.25dB/cm and 0.27dB/cm.respectively.The strength of chalcoge nide glass fiber protected by a thin layer of plastic polymer is 1.45times of t hat of a standard silica fiber,promoting the development of chalcogenide glass m icro-structure optical fibers.