Interference light fields of general Laguerre-Gaussian vortex beam and off-axis vortex Laguerre-Gaussian beam are simulated theoretically in this pa pe r.By comparing and analyzing the simulation parameters,it is shown that the li ght intensity distribution of interference pattern of off-axis vortex beam is a s ymmetric,and the light distributions with the same or different topological char ges are focused to one direction.With the same topological charge,the asymmetr ic phenomenon of light intensity distribution pattern is more obvious,as the of f-axis parameter d is changing.When the topological cha rges are different,to t he interference of general vortex beam,only the circumference spreading of the l ight spot is affected,and when off-axis vortex beams with different topologica l charges interfere,it is identical to general vortex beam interference,and th e positive or negative topological charge determines the direction of the light field concentration distribution.When the topological charge and off-axis param eter are fixed values,the width of light spot on the observation surface wil l increase accordingly with increasing the transmission distance.The simulation results show that this method is beneficial to the long distance observation of vortex beam interference alignment,and the analysis results are significant fo r trapping and manipulating micro-particles by using vortex beams.