Boron-doped diamond (BDD) thin film e lectrode was made in hydrogen-argon carbon source by direct current (DC) plasm a jet chemical vapor deposition (CVD) method,and surface uniform and dense distr ibution can be seen by scanning electro microscopy (SEM).The resistivity is 0.023Ω·cm by the Hall test cytometry,and carrier concentration is 6.423×10¹⁹ cm－3.The potential window for electrode is 3.4V measured by cyclic voltammetry (CVa),and the boron-doped diam ond thin-film electrode′s electrochemical response is analyzed at 10μmol/L o f uric acid (UA).The scan rate is linear with oxidation peak current.In Alizarin yellow,taurine and L-cysteine modified BDD electrodes,the last one has the str ongest electrocatalytic oxidation.The experimental results show that when the co ncentration of UA within the range of 1×10－7－1×10－4 mol/L,the logarithm of the concentrationt is linear with the oxidation peak current,and t he detection limit is 1×10－8 mol/L.The 20-fold concentration of g lucose and ascorbic acid does not affect th e detection of uric acid.