The gold hollow-core semi-shell nanostructures with different locali zed surface plasmon resonance (LSPR) properties were fabricated by nanolithography technique through depositin g gold film onto a cleaned glass support covered with a close-packed monolayer of 200nm diameter polystyrene (P S) sp heres and subsequently by the removal of the PS spheres.The optical properties of gold nanostructures can be controlled by the deposition time. Then,using 4-aminothiophenol (4-ATP) as the probe molecule,the surface enhan ced Raman scattering (SERS) signals of 4-ATP adsorbed on the gold nanostructures with different LSPR peak w avelengths were measured by Raman spectroscopy.The changes of SERS properties due to different number of ad sorbed 4-ATP molecules are experimentally investigated.The results show that the SERS signal intensities d epend on the LSPR properties of metal nanostructures and the numbers of adsorbed molecules.In the case of LSPR p eak wavelength of the nanostructures located at the left side of ideal excitation wavelength arrangeme nt or saddle type arrangement, the SERS intensity increases monotonically with the number of adsorbed molecules ,the SERS intensity increases first and then decreases if the LSPR peak wavelength located at right side of th e excitation wavelength.The changes of SERS intensities are ascribed to the local electric field excited by incident light and molecule adsorbed theory.