A high speed and high reliability transmission system applicable to th e high resolution and large field time delay and integration charge-coupled dev ice (TDICCD) camera is proposed.First,this paper analyzes the communication link TLK2711and presents a high-speed serial transmission strategy based on synchronous control word.Then,the (17,6) error correction coding algorithm i s put forward on basis of the in-depth analysis of the impact of noise on the transmission reliability.The thought and correction theo ry of the proposed algorithm is explained and its feasibility of application for large field space camera is demonstrated. This algori thm is tested on a multi-spectral space camera and the results show that the system can achieve the transmission of 80route data with the effective data throughput of up to 13.02Gbit/s for the whole system.It is verified that the (17,6) error correction coding algori thm has the characteristics of strong correction ability,high calculation speed and easy implementation in hardware.It improves the reliabili ty of space camera high-speed serial transmission with the ability that each 512byte data can correct as many as 32bit errors.I n conclusion,the system has obtained satisfactory effect under different transmission speeds with good portability,which is able to meet the real-time,high-speed and reliable image transmission requirements for the high spatial resolution TDICCD camera wi th large field of view.