In order to unify the measuring coordinates between portable structured light measuring system and optical three- coordinate measuring system,a global calibration method based on eye-to-hand model is proposed in this paper.A planar target fixed to the global measuring system and a stereo target with acti ve light fixed rigidly to the portable structured light measuring system are using as intermediate coordinates.Firstly ,the pose parameters between planar target and portable structured light measuring system and between stereo target and optical three coordinate measuring system are estimated.Secondly,the pose parame ter between stereo target and portable structured light measuring system is computed based on the eye-to-hand model.Consequentl y,the measuring coordinate systems between portable structured light measuring system and optical three coo rdinate measuring system is unified globally.The experimental results show that the error standard deviation of cali bration results is about 0.151mm and the accuracy of results is reasonable and efficient.Therefore,it verifies that the calibration method proposed in this paper is efficient,fast and well suited to the calibration work of unifying the coordinates for portable combined measuring system.